SCALING BLOCKCHAIN FOR AGRICULTURAL SECTOR: THE AGRIDIGITAL CASE

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In Vitro Effects of Strontium on Proliferation and Osteoinduction of Human Preadipocytes.

Development of tools to be used for in vivo bone tissue regeneration focuses on cellular models and differentiation processes. In searching for all the optimal sources, adipose tissue-derived mesenchymal stem cells (hADSCs or preadipocytes) are able to differentiate into osteoblasts with analogous characteristics to bone marrow mesenchymal stem cells, producing alkaline phosphatase (ALP), collagen, osteocalcin, and calcified nodules, mainly composed of hydroxyapatite (HA). The possibility to influence bone differentiation of stem cells encompasses local and systemic methods, including the use of drugs administered systemically. Among the latter, strontium ranelate (SR) represents an interesting compound, acting as an uncoupling factor that stimulates bone formation and inhibits bone resorption. The aim of our study was to evaluate the in vitro effects of a wide range of strontium (Sr2+) concentrations on proliferation, ALP activity, and mineralization of a novel finite clonal hADSCs cell line, named PA20-h5. Sr2+ promoted PA20-h5 cell proliferation while inducing the increase of ALP activity and gene expression as well as HA production during in vitro osteoinduction. These findings indicate a role for Sr2+ in supporting bone regeneration during the process of skeletal repair in general, and, more specifically, when cell therapies are applied

La internacionalización de la actividad innovativa en las empresas multinacionales: un análisis geográfico y sectorial

Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Económicas y Empresariales, Departamento de Economía Aplicada II (Estructura Económica y Economía Industrial), leída el 21-11-2014Depto. de Economía Aplicada, Estructura e HistoriaFac. de Ciencias Económicas y EmpresarialesTRUEunpu

Economia per l’integrazione culturale e la coesione sociale

No abstract availabl

Multinational enterprise and knowledge flows: a case study

Proceedings of the Second Globelics Academy, Lisbon, Portugal, 23 May - 3 June 2005

Introduzione all'economia della società

No abstract availabl

La smart specialisation strategy in Italia : limiti e traiettorie

No abstract availabl

Global value chains in the era of 4IR: new paradigm of business models for SMEs

This paper presents a brief literature review of previous studies methodologies, models, and contexts in studying firms’ upgrading in Global Value Chains (GVCs). The key context of this paper is set within Fourth Industrial Revolution (4IR). Through the literature review, this paper offers to identify the opportunities of theoretical novelty and ways to elaborate on understanding firm dynamics in Global Value Chains in the context of 4IR. The approach based on Business Model (BM) innovations and new forms of organizing for business (such as platforms) is used to synthesize from previous research findings and build on to newer explanations of firms’ entry, learning, and upgrading within GVCs

Le politiche regionali di innovazione in Italia : prospettive verso Horizon 2020

No abstract availabl